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Triphasic waves in a patient with tuberculous meningitis

2010; Elsevier BV; Volume: 291; Issue: 1-2 Linguagem: Inglês

10.1016/j.jns.2009.12.027

1878-5883

Shingo Konno, Hideki Sugimoto, Hiroshi Nemoto, Hisao Kitazono, Mayumi Murata, Takahiro Toda, Hiroshi Nakazora, Nobuatsu Nomoto, Nobuo Wakata, Teruyuki Kurihara, Toshiki Fujioka,

Neuroscience and Neuropharmacology Research

We report on the case of a 32-year-old woman with tuberculous meningitis (TBM) with electroencephalogram (EEG) output displaying triphasic waves (TWs). The EEG on day 8 revealed generalized slowing, frontal bilateral TWs, a background of 2Hz delta waves, and no epileptiform activity. The patient's condition improved slowly with antituberculosis chemotherapy treatment. A follow-up EEG on day 34 showed marked improvement, with no TWs, background activity improved to a 12Hz symmetric alpha wave pattern, and no epileptiform activity, as before. To our knowledge, this is the first report of TWs observed in a TBM case.