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Postural Proteinuria

1966; American College of Physicians; Volume: 65; Issue: 2 Linguagem: Inglês

10.7326/0003-4819-65-2-286

1539-3704

Roger Herdman,

Coagulation, Bradykinin, Polyphosphates, and Angioedema

Article1 August 1966Postural ProteinuriaResponse to Corticosteroid TherapyROGER C. HERDMAN, M.D., ALFRED F. MICHAEL, M.D., ROBERT A. GOOD, M.D.ROGER C. HERDMAN, M.D.Search for more papers by this author, ALFRED F. MICHAEL, M.D.Search for more papers by this author, ROBERT A. GOOD, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-65-2-286 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptWe recently had an opportunity to study a child (Case 1) with a history of the steroid responsive nephrotic syndrome who developed postural proteinuria which also disappeared after a course of corticosteroid therapy. Although the status of postural proteinuria as a significant renal abnormality is uncertain, the case history of this child suggested to us that there might be some relationship or similarity between postural proteinuria and the idiopathic nephrotic syndrome of childhood. Both conditions are characterized by proteinuria occurring predominantly in the younger age groups, by lack of significant renal histologic abnormalities by light microscopy, and usually by a...References1. HILLERGRIEFBECKMAN ARLWW: Determination of protein in urine by the biuret method. J. Biol. Chem. 176: 1421, 1948. CrossrefMedlineGoogle Scholar2. MICHAELDRUMMONDGOODVERNIER AFKNRARL: Acute poststreptococcal glomerulonephritis: immune deposit disease. J. Clin. Invest. 45: 237, 1966. CrossrefMedlineGoogle Scholar3. ROBINSONGLOVERPHILLIPPILECOCQLANGELIER RRSNPJFRPR: Fixed and reproducible orthostatic proteinuria. I. Light microscopic studies of the kidney. Amer. J. Path. 39: 291, 1961. MedlineGoogle Scholar4. ROBINSONLECOCQPHILLIPPIGLENN RRFRPJWG: Fixed and reproducible orthostatic proteinuria. III. Effect of induced renal hemodynamic alterations upon urinary protein excretion. J. Clin. Invest. 42: 100, 1963. CrossrefMedlineGoogle Scholar5. LATHEM W: Renal circulatory dynamics and urinary protein excretion during infusions of l-norepinephrine and l-epinephrine in patients with renal disease. J. Clin. Invest. 35: 1277, 1956. CrossrefMedlineGoogle Scholar6. KING SE: Postural adjustments and protein excretion by the kidney in renal disease. Ann. Intern. Med. 46: 360, 1957. LinkGoogle Scholar7. LATHEMROOFNICKELBRADLEY WBSSFSE: Urinary protein excretion and renal hemodynamic adjustments during orthostasis in patients with acute and chronic renal diseases. J. Clin. Invest. 33: 1457, 1954. CrossrefMedlineGoogle Scholar8. MUTH RG: Asymptomatic mild intermittent proteinuria. Arch. Intern. Med. (Chicago) 115: 569, 1965. CrossrefMedlineGoogle Scholar9. KINGBALDWIN SEDS: Renal hemodynamics during erect lordosis in normal man and subjects with orthostatic proteinuria. Proc. Soc. Exp. Biol. Med. 86: 634, 1954. CrossrefMedlineGoogle Scholar10. ROBINSONGLENN RRWG: Fixed and reproducible orthostatic proteinuria. IV. Urinary albumin excretion by healthy human subjects in the recumbent and upright postures. J. Lab. Clin. Med. 64: 717, 1964. MedlineGoogle Scholar11. ROBINSONASHWORTHGLOVERPHILLIPPILECOCQLANGELIER RRCTSNPJFRPR: Fixed and reproducible orthostatic proteinuria. II. Electron microscopy of renal biopsy specimens from five cases. Amer. J. Path. 39: 405, 1961. MedlineGoogle Scholar12. FRANKLIN EC: Physicochemical and immunologic studies of gamma globulins of normal human urine. J. Clin. Invest. 38: 2159, 1959. CrossrefMedlineGoogle Scholar13. MCKAYSLATER ERJ: Studies of human proteinuria. II. Some characteristics of the gamma globulins excreted in normal, exercise, postural, and nephrotic proteinuria. J. Clin. Invest. 41: 1638, 1962. CrossrefMedlineGoogle Scholar14. KING SE: Albuminuria (proteinuria) in renal diseases. II. Preliminary observations on the clinical course of patients with orthostatic albuminuria. New York J. Med. 59: 825, 1959. MedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Minneapolis, MinnesotaFrom the Pediatric Research Laboratories, Variety Club Heart Hospital, and the Department of Pediatrics, University of Minnesota, Minneapolis, Minn.This study was supported in part by a grant from the American Heart Association, grants HE-05662, HE-06314, and 2-F2-AM-19-212-03, U. S. Public Health Service, Bethesda, Md., and by the National Foundation, New York, N. Y.Dr. Herdman is a Postdoctoral Research Fellow of the U. S. Public Health Service. Dr. Michael is an Established Investigator of the American Heart Association. Dr. Good is an American Legion Memorial Heart Research Professor of Pediatrics and Microbiology.Requests for reprints should be addressed to Roger Herdman, M.D., Department of Pediatrics, University of Minnesota Hospitals, Minneapolis, Minn. 55455. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byOrthostatic proteinuria and milk ingestionProteinuria: Diagnostic Principles and ProceduresJ. GARY ABUELO, M.D.Asymptomatic proteinuriaPediatric renal diseaseARE PROTEINURIA TESTS RELIABLE AS SCREENING METHODS FOR RENAL DISEASE? 1 August 1966Volume 65, Issue 2Page: 286-292KeywordsAge groupsCorticosteroid therapyHeartLight microscopyLongitudinal studiesMedical servicesMicrobiologyProteinsProteinuriaResearch laboratories ePublished: 1 December 2008 Issue Published: 1 August 1966 PDF downloadLoading ...