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Production of Magnetic Nanoparticles in Imine Polymer Matrixes

2000; American Chemical Society; Volume: 12; Issue: 12 Linguagem: Inglês

10.1021/cm0011561

1520-5002

Cristina Castro, José Ángel Ramos, Ángel Millán, J.M. González-Calbet, Fernando Palacio,

Nanoparticle-Based Drug Delivery

Nanocomposites showing superparamagnetic properties have been synthesized from imine polymers. The method for the production of the nanocomposites is very simple. The imine polymer reacts with a metal salt and the product is dried. Apparently, the reaction of polymer grains with a metal solution takes place by a surface reaction mechanism. Metal hydroxides precipitate within the polymer matrix without addition of a base or of an oxidizer since the polymer imine groups provide a basic medium. The metal oxides are formed through hydrolysis of the metal hydroxides when drying. The method works the best for imine polymers with a flexible chain and no hydrophobic branches. Several iron and cobalt salts, as well as a manganese salt, have been used in the procedure. The effect of the solvent and of the metal salt counterion on the procedure has been studied.