Striatal dopamine after cortical injury: A reexamination
1987; Elsevier BV; Volume: 97; Issue: 1 Linguagem: Inglês
10.1016/0014-4886(87)90295-0
ISSN1090-2430
AutoresJennika Veinot, Marc R. Peterson, H.A. Robertson,
Tópico(s)Pain Mechanisms and Treatments
ResumoWe reevaluated the effects of unilateral sensorimotor cortex ablation on dopamine and dihydroxyphenylacetic acid concentrations in the left and right neostriatum. We found no evidence for an asymmetry of either dopamine or dihydroxyphenylacetic acid in control or sham-operated animals and cortical ablation had no effect on dopamine or dihydroxyphenylacetic acid concentrations. These results suggest that the influence of sensorimotor cortex lesions on extrapyramidal function does not involve changes in striatal dopamine concentrations or turnover.
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