Aberrant morphology of platelets stored in five day containers
1984; Elsevier BV; Volume: 33; Issue: 6 Linguagem: Inglês
10.1016/0049-3848(84)90115-4
ISSN1879-2472
AutoresJoseph C. Fratantoni, Brenda Sturdivant, Betty J. Poindexter,
Tópico(s)Hemoglobin structure and function
ResumoAbstract Platelets for transfusion, stored in either of two new types of container (PL-732 and CLX), demonstrated unusual morphological alterations after 2 or 3 days of storage. The atypical forms observed included crescents, elongated tubular forms and rings. Development of these forms was not seen if the permeability of the container was inhibited and the pH kept below 6.7. The variables which differentiate these new containers from those previously used, and which appear to be related to the changes described, are pH, pO 2 and presence of a leachable plasticizer. The functional behaviour of these platelets, as assessed by serotonin uptake and resistance to hypotonic shock, was not different from that of control platelets.
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