Portal de Periódicos da CAPES

Positron emission tomography: applications to the investigation of movement disorders

1994; Wiley; Volume: 24; Issue: 7 Linguagem: Inglês

10.1111/j.1365-2362.1994.tb02371.x

1365-2362

E. Diane Playford,

Advanced MRI Techniques and Applications

European Journal of Clinical InvestigationVolume 24, Issue 7 p. 433-440 Positron emission tomography: applications to the investigation of movement disorders E. D. PLAYFORD, Corresponding Author E. D. PLAYFORD MRC Cycloton Unit, Hammersmith Hospital, DuCane Road, London, UKMRCP, MRC Cycloton Unit, Hammersmith Hospital, DuCane Road, London W12 0HS, UK.Search for more papers by this author E. D. PLAYFORD, Corresponding Author E. D. PLAYFORD MRC Cycloton Unit, Hammersmith Hospital, DuCane Road, London, UKMRCP, MRC Cycloton Unit, Hammersmith Hospital, DuCane Road, London W12 0HS, UK.Search for more papers by this author First published: July 1994 https://doi.org/10.1111/j.1365-2362.1994.tb02371.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL References 1 Hounsfield GN. Computerised transverse axial scanning (tomography): Part 1. Description of system. Br J Radiol 1973; 46: 1016– 22. 2 Derenzo SE. Precision measurements of annihilation point spread distributions for medically important positron emitters. Proceedings 5th International Conference on Positron Annihilation 1979; 819– 23. 3 Evans RD. The Atomic Nucleus. Malabar, Florida: R.E. Krieger, 1955. 4 Camici PG, Ferannini E, Opie LH. Myocardial metabolism in ischemic heart disease: basic principles and applications to imaging by positron emission tomography. Prog Cardiovasc Dis 1989; 32: 217– 38. 5 Jones T, Tilsley DWO, Wilson CBJH et al. Positron emission tomography for tumour assessment. NMR Biomed 1992; 5: 265– 9. 6 Greenberg J, Hand P, Sylvestro A, Reivich M. Localised metabolic-flow couple during functional activity. J Cereb Blood Flow Metab 1979;Suppl 1– 6 (Abstract). 7 Lueck CJ, Zeki S, Friston KJ et al. The colour centre in the cerebral cortex of man. Nature 1989; 340: 386– 9. 8 Olesen J. Contralateral focal increase of cerebral blood flow in man during arm work. Brain 1971; 94: 635– 46. 9 Roland PE, Larsen B, Lassen NA, Skinhoj E. Supplementary motor area and other cortical areas in organization of voluntary movements in man. J Neurophysiol 1980a; 43: 118– 36. 10 Roland PE, Skinhoj E, Lassen NA, Larsen B. Different cortical areas in man in organization of voluntary movements in extrapersonal space. J Neurophysiol 1980b; 43: 137– 50. 11 Roland PE, Meyer E, Shibasaki T, Yamamoto YL, Thompson CJ. Regional cerebral blood flow changes in cortex and basal ganglia during voluntary movements in normal human volunteers. J Neurophysiol 1982; 48: 467– 79. 12 Colebatch JG, Deiber M-P, Passingham RE, Friston KJ, Frackowiak RSJ. Regional cerebral blood flow during voluntary arm and hand movements in human subjects. J Neurophysiol 1991; 65: 1392– 401. 13 Zeffiro T, Hallett M. Topographic organisation of cortical motor areas: a PET study. Movement Disorders 1992; 7,(Suppl. 1): (Abstract) 139. 14 Deiber M-P, Passingham RE, Colebatch JG, Friston KJ, Nixon PD, Frackowiak RSJ. Cortical areas and the selection of movements: a study with positron emission tomography. Exp Brain Res 1991; 84; 393– 402. 15 Jenkins IH, Brooks DJ, Nixon PD, Frackowiak RSJ, Passingham RE. Motor sequence learning: A study with positron emission tomography. J Neurosci 1994;In press. 16 Friston KJ, Frith CD, Passingham RE, Liddle PF, Frackowiak RSJ. Motor practice and neurophysiological adaptation in the cerebellum: a positron tomography study. Proceedings of the Royal Society of London 1992; 248: 223– 8. 17 Playford ED, Jenkins IH, Passingham RE, Nutt J, Frackowiak RSJ, Brooks DJ. Impaired mesial frontal and putamen activation in Parkinson's disease: a positron emission tomography study. Ann Neurol 1992; 32: 151– 61. 18 Goldberg G. Supplementary motor area structure and function: review and hypotheses. Behav Brain Sci 1985; 8: 567– 616. 19 Passingham RE. Two cortical systems for directing movement. In Motor Areas of the Cerebral Cortex. Ciba Foundation 1987; 132: 151– 64. 20 Jenkins IH, Fernandez W, Playford ED et al. Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine. Ann Neurol 1992; 32: 749– 57. 21 Sawle GV, Lees AJ, Hymas NF, Brooks DJ, Frackowiak RSJ. The metabolic effects of limbic leucotomy in Gilles de la Tourette syndrome. J Neurol Neurosurg Psychiatry 1993; 56: 1016– 19. 22 Kuhl DE, Phelps ME, Markham CH, Metter, Riege WH, Winter J. Cerebral metabolism and atophy in Huntington's disease determined by 18FDG and computed tomographic scan. Ann Neurol 1982; 12: 425– 34. 23 Mazziotta JC, Phelps ME, Pahl JJ et al. Reduced cerebral glucose metabolism in asymptomatic subjects at risk for Huntington's disease. New Engl J Med 1987; 316: 357– 62. 24 Grafton ST, Mazziotta JC, Pahl JJ et al. A comparison of neurological, metabolic, structural and genetic evaluations in persons at risk for Huntington's disease. Ann Neurol 1990; 28: 614– 21. 25 The Huntington's Disease Collaborative Research Group. A novel gene containing a tri-nucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993; 72: 971– 83. 26 Garnett ES, Firna G, Chan PKH, Sood S, Belbeck CK. [18F]Fluorodopa, an analogue of dopa and its use in direct external measurements of storage, degradation and turnover of intracebral dopamine. Proc Nat Acad Sci USA 1978; 75: 464– 7. 27 Firnau G, Garnett ES, Chan PKH, Belbeck LW. Intracerebral dopamine metabolism studied by a novel radioisotope technique. J Pharm Pharmacol 1976; 30: 584– 5. 28 Garnett ES, Firnau G, Nahmias C, Chirakal R (1983b) Striatal dopamine metabolism in living monkeys examined by positron emissiontomography. Brain Res 1983b; 280: 169– 71. 29 Diffley DM, Costa JL, Sokoloski EA, Chiueh CC, Kirk KL, Creveling CR. Direct observation of 6-fluorodopamine in guinea pig nerve microsacs by 19F NMR. Biochem Biophys Res Comm 1983; 110: 740– 5. 30 Salmon EP, Brooks DJ, Leenders KL et al. A two compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography. J Cereb Blood Flow Metab 1980; 10: 807– 16. 31 Garnett ES, Firnau G, Nahmias C. Dopamine visualised in the basal ganglia of living man. Nature 1983a; 305: 137– 8. 32 Garnett ES, Nahmias C, Firnau G. (1984) Central dopaminergic pathways in hemiparkinsonism examined by positron emission tomography. Can Neurol Sci 1984; 11: 174– 9. 33 Garnett ES, Nahmias C, Firnau G, Lang W, Chieuh CM. DA metabolism in Parkinson's disease. J Cereb Blood Flow Metab 1985; 5: Suppl 1, S159. 34 Nahmias C, Garnett ES, Firnau G, Lang A. Striatal dopamine distribution in parkinsonian patients during life. J Neurol Sci 1985; 69: 223– 30. 35 Brooks DJ, Ibanez V, Sawle GV et al. Differing patterns of striatal 18F-Dopa uptake in Parkinson's disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. Ann Neurol 1990; 28: 547– 55. 36 Hoehn MM, Yahr MD. Parkinsonism: onset, progression and mortality. Neurology 1967; 17: 427– 42. 37 Hughes AJ, Daniel JE, Kilford L, Lees AJ. Accuracy of clinical diagnosis of Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992; 55: 181– 4. 38 Fearnley JM, Revesz T, Brooks DJ, Frackowiak RSJ, Lees AJ. Diffuse Lewy body disease presenting with a supranuclear gaze palsy. J Neurol Neurosurg Psychiatr 1991; 54: 159– 61. 39 Graham JG, Oppenheimer DR. Orthostatic hypotension and nicotine sensitivity in a case of multiple system atrophy. J Neurol Neurosurg Psychiatry 1969; 32: 28– 34. 40 Shy MG, Drager GA. A neurological syndrome associated with orthostatic hypotension. Arch Neurol 1960; 2: 511– 27. 41 Spokes EGS, Bannister R, Oppenheimer DR. Multiple system atrophy with autonomic failure. Clinical, histological, and neurochemical observations on four cases. J Neurol Sci 1979; 43: 59– 62. 42 Quinn N. Multiple system atrophy—the nature of the beast. J Neurol Neurosurg Psychiatry 1989;Suppl: 78– 89. 43 Thapedi IM, Ashenhurst EM, Rozdilsky B. (1979) Shy-Drager Syndrome: report of an autopsied case. Neurol 1971; 21: 26– 32. 44 Steele JC, Richardson JC, Olszewski J. Progressive supranuclear palsy. A heterogeneous degeneration involving the brain stem, basal ganglia, and cerebellum with vertical gaze and pseudobulbar palsy, nuchal dystonia, and dementia. Arch Neurol 1964; 10: 333– 58. 45 Jellinger K, Riederer P, Tomanaga M. Progressive supanuclear palsy: clinico-pathological and biochemical studies. Neural Trans 1980; Suppl 16: 111– 28. 46 Bhatt MH, Snow BJ, Martin WRW, Cooper S, Calne DB. Positron emission tomography in Shy—Drager syndrome. Ann Neurol 1990; 28: 101– 3. 47 Brooks DJ, Ibanez V, Sawle GV et al. Striatal D2 receptor status in Parkinson's disease, striato-nigral degeneration, and progressive supranuclear palsy measured with 11C raclopride and PET. Ann of Neurol 1992; 31: 184– 92. 48 Leenders KL, Salmon EP, Tyrell PJ et al. Brain-L-[18F]-6-fluorodopa and [11C]-nomifensine uptake in patients with Parkinson's disease and healthy volunteers. J Cereb Blood Flow Metab 1989; 9: S722. 49 Sawle GV, Brooks DJ, Ibanez V, Frackowiak RSJ. Striatal D2 receptor density is inversely proportional to dopa uptake in untreated hemi-parkinsons disease: a positron emission tomography study. J Neurol Neurosurg Psychiatry 1990a; 53: 177– 82. 50 Rinne UK, Laihinen A, Rinne JO, Nagren K, Bergman J, Ruotsalainen U. Positron emission tomography demonstrates dopamine D2 receptor supersensitivity in the striatum of patients with early Parkinson's disease. Mov Disord 1990; 5: 55– 9. 51 Hagglund J, Aquilonius S-M, Eckernas S-A et al. Dopamine receptor properties in Parkinson's disease and Huntington's chorea evaluated by positron emission tomography using 11C-N-methyl-spiperone. Acta Neurol Scand 1987; 75: 87– 94. 52 Wienhard K, Coenen HH, Pawlik G et al. PET studies of dopamine receptor distribution using [18F]fluoroethylspiperone: findings in disorders related to the dopaminergic system. J Neural Transm 1990; 81: 195– 213. 53 Rutgers AWF, Lakke JPWF, Paans AMJ, Vallburg W, Korf J. Tracing of dopamine receptors in hemiparkinsonism with positron emission tomography (PET). J Neurolog Sci 1987; 80: 237– 48. 54 Baron JC, Maziere B, Loch C et al. Loss of striatal [76Br]bromospiperone binding sites demonstrated by positron tomography in progressive supranuclear palsy. J Cereb Blood Flow Metab 1986; 6: 131– 6. 55 Burn DJ, Mathias CJ, Quinn N, Marsden CD, Brooks DJ. Striatal opiate receptor binding in Parkinson's disease and multiple system atrophy: An [11C]diprenorphine study. Neurology 1993; 43: 454S. 56 Sawle GV, Colebatch JG, Shah A, Brooks DJ, Marsden CD, Frackowiak RSJ. (1990b) Striatal function in normal aging: implications for Parkinson's disease. Ann Neurol 1990b; 28: 799– 804. 57 Martin WRW, Palmer MR, Patlak CS, Calne DB. Nigrostriatal function in humans studied with positron emission tomography. Ann Neurol 1989; 26: 535– 42. 58 Degl'innocenti F, Maurello MT, Marini P. A parkinsonian kindred. Ital J Neurol Sci 1989; 10: 307– 10. 59 Duvoisin RC. The genetics of Parkinson's disease: a review. Adv Neurol 1993; 60: 306– 15. 60 Bundey S. Uses and limitations of twin studies. J Neurol 1991; 238: 360– 64. 61 Forno LS. The Lewy body in Parkinson's disease. Adv Neurol 1986; 45: 35– 43. 62 Golbe LI. The genetics of Parkinson's disease: a reconsideration. Neurology 1990; 40(Suppl 3): 7– 14. 63 Guttman M, Yong VW, Kim SU et al. Asymptomatic striatal dopamine depletion: PET scans in unilateral MPTP monkeys. Synapse, 1988; 2: 469– 73. 64 Snow BJ, Peppard RF, Guttman M et al. Positron emission tomographic scanning demonstrates a presynaptic dopaminergic lesion in Lytico-Bodig. Arch Neurol 1990; 47: 870– 4. 65 Burn DJ, Mark MH, Playford ED et al. Parkinson's disease in twins studies with [18F]dopa and positron emission tomography. Neurology 1992; 42: 1894– 900. 66 Lindvall O, Backlund E-O, Farde L et al. Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen. Ann Neurol 1987; 22: 457– 68. 67 Guttman M, Burns RS, Martin WR et al. PET studies of parkinsonian patients treated with autologous adrenal implants. Can J Neurol Sci 1989; 16: 305– 9. 68 Lindvall O, Rehncrona S, Brundin P et al. (1989) Human fetal dopamine neurones grafted into the striatum of in two patients with severe Parkinson's disease. A detailed account of the methodology, and a six month follow-up. Arch Neurol 1989; 46: 615– 31. 69 Lindvall O, Widner H, Rehncrona S et al. Transplantation of fetal dopamine neurons in Parkinson's disease: One year clinical and neurophysiological observation in two patients with putaminal implants. Ann Neurol 1992; 31: 155– 65. 70 Sawle GV, Bloomfield PM, Bjorklund A et al. Transplantation of fetal dopamine neurons in Parkinson's disease: PET [18F]6-L-Fluorodopa studies in two patients with putaminal implants. Ann Neurol 1992; 31: 166– 73. 71 Bhatt MH, Snow BJ, Martin WRW, Pate BD, Ruth TJ, Calne DB. Positron emission tomography suggests that the rate of progression of idiopathic parkinsonsism is slow. Ann Neurol 1991; 29: 673– 7. 72 Sawle GV. The rate of progression of Parkinson's disease. [Letter] Ann Neurol 1992; 31: 229. 73 Sawle GV, Turjanski N, Brooks DJ, Frackowiak RSJ. The rate of disease progression in Parkinson's disease: PET findings in patients receiving medical treatment or following foetal mesencephalic transplantation. Neurology 1992; 44: 542. Volume24, Issue7July 1994Pages 433-440 ReferencesRelatedInformation