Saframycin synthetic studies
1991; Elsevier BV; Volume: 47; Issue: 30 Linguagem: Inglês
10.1016/s0040-4020(01)86518-2
ISSN1464-5416
AutoresT. T. SHAWE, Liebeskind Lanny S,
Tópico(s)Marine Sponges and Natural Products
ResumoA conceptually simple and direct synthetic route to racemic saframycyn B, a bis-isoquinoline quinone antitumor antibiotic, was studied relying on transformations of a key C-2 symmetric intermediate.
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