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Pharmacological Effects of Rutaecarpine, an Alkaloid Isolated from Evodia rutaecarpa

1999; Wiley; Volume: 17; Issue: 3 Linguagem: Inglês

10.1111/j.1527-3466.1999.tb00017.x

1527-3466

Jin‐Chuan Sheu,

Oxidative Organic Chemistry Reactions

Cardiovascular Drug ReviewsVolume 17, Issue 3 p. 237-245 Free Access Pharmacological Effects of Rutaecarpine, an Alkaloid Isolated from Evodia rutaecarpa Joen-Rong Sheu, Corresponding Author Joen-Rong Sheu Graduate Institute of Medical Sciences & Department of Pharmacology, Taipei Medical College, Taipei, TaiwanAddress correspondence to Dr. Joen-Rong Sheu, Graduate Institute of Medical Sciences, Taipei Medical College, 250, Wu-Shing Street, Taipei 110, Taiwan. Tel/Fax: +866-2-27390450, E-mail: sheujr@tmc.edu.twSearch for more papers by this author Joen-Rong Sheu, Corresponding Author Joen-Rong Sheu Graduate Institute of Medical Sciences & Department of Pharmacology, Taipei Medical College, Taipei, TaiwanAddress correspondence to Dr. Joen-Rong Sheu, Graduate Institute of Medical Sciences, Taipei Medical College, 250, Wu-Shing Street, Taipei 110, Taiwan. Tel/Fax: +866-2-27390450, E-mail: sheujr@tmc.edu.twSearch for more papers by this author First published: 07 June 2006 https://doi.org/10.1111/j.1527-3466.1999.tb00017.xCitations: 34AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Liao JF, Chen CF, Chow SY. Pharmacological studies of Chinese herbs. (9) Pharmacological effects of Evodiae fructus. J Formosan Med Assoc 1981; 79: 30– 38. 2 Chow SY, Chen SM, Yang CM. Pharmacological studies on Chinese herbs (3). Analgesic effect of 27 Chinese drugs in mice. J Formosan Med Assoc. 1976; 75: 349– 357. 3 Chen CF, Chen SM, Lin MT, Chow SY. In vivo and in vitro studies on the mechanism of the cardiovascular effect of Wu-Chu-Yu (Evodiae furctus). Am J Chin Med 1981; 1: 39– 47. 4 Tschesche R, Werner W. Evocarpine, anew alkaloid from Evodia rutaecarpa. Tetrahedron 1967; 23: 1873– 1881. 5 Kurono G, Aburano S, Yamada N, Nishikawa Y. Studies on fatty acids from fruit and seed oils. 4. Analysis of the fatty acid composition in fruits of Evodia rutaecarpa of Chinese origin. Yakugaku Zasshi-J Pharm Soc Jpn. 1973; 93: 691– 692. 6 Yang HY, Li SY, Chen CF. Hypotensive effects of dehydroevodiamine, a quinazolinocarboline alkaloid isolated from Evodia rutaecarpa. Asia Pacific J Pharmacol 1988; 3: 191– 195. 7 Yang MC, Wu SL, Kao JS, Chen CF. The hypotensive and negative chronotropic effect of dehydroevodiamine. Eur J Pharmacol 1990; 182: 537– 542. 8 Shoji N, Umeyama A, Takemoto T, Kajiwara A, Ohizumi Y. Isolation of evodiamine, a powerful cardio-tonic principle, from Evodia rutaecarpa Bentham (Rutaceae). J Pharm Sci 1986; 75: 612– 613. 9 Yamahara J, Yamada T, Kitani T, Naiton Y, Fujimura H. Antianoxic action of evodiamine, an alkaloid in Evodia rutaecarpa fruit. J Ethnopharmacol 1989; 27: 185– 192. 10 Chiou WF, Chou CJ, Shum AYC, Chen CF. The vasorelaxant effect of evodiamine in rat isolated mesenteric arteries: Mode of action. Eur J Pharmacol 1992; 215: 277– 283. 11 Chiou WF, Chou CJ, Liao JF, Sham AYC, Chen CF. The mechanism of the vasodilator effect of rutae-carpine, and alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol 1994; 257: 59– 66. 12 Sheu JR, Kan YC, Hung WC, et al. The antiplatelet activity of rutaecarpine, an alkaloid isolated from Evodia rutaecarpa, is mediated through inhibition of phospholipase C. Thromb Res 1998; 92: 53– 64. 13 Kametani T, Loc CV, Higa T, Koizumi M, Ihara M, Fukumoto K. Iminoketene cycloaddition. 2.1 Total synthesis of arborine, glycosamine, and rutaecarpine by condensation of iminoketene with amides. J Am Chem Soc 1977; 99: 2306– 2309. 14 Rees DD, Palmer RMJ, Hodson HF, Moncada S. A specific inhibitor of nitric oxide formation from L-arginine attenuates endothelium-dependent relaxation. Br J Pharmacol 1989; 96: 418– 424. 15 Martin W, Villani GM, Furchgott RF. Hemoglobin and methylene blue selectively inhibit relaxation of rabbit aorta by agents which increase cyclic GMP levels. Fed Proc (Abs) 1984; 3: 737. 16 Satoh H, Inui J. Endothelial cell-dependent relaxation and contraction induced by histamine in the isolated guinea-pig pulmonary artery. Eur J Pharmacol 1984; 97: 321– 324. 17 Vanhoutte PM. Endothelium and control of vascular function. Hypertension 1989; 13: 658– 667. 18 Chiou WF, Shum AYC, Liao JF, Chen CF. Studies of the cellular mechanisms underlying the vasorelaxant effects of rutaecarpine, a bioactive component extracted from an herbal drug. J Cardiovasc Pharmacol 1997; 29: 490– 498. 19 Bigay J, Deterre P, Pfister C, Chabre M. Fluoride complexes of aluminium or beryllium act on G-proteins as reversibly bound analogues of the gamma-phosphate of GTP. EMBO J 1987; 6: 2907– 2913. 20 Smith RJ, Sam LM, Justen JM, Bundy GL, Bala GA, Bleasdale JE. Receptor-coupled signal transduction in human polymorphonuclear neutrophils: effects of a novel inhibitor of phospholipase C-dependent processes on cell responsiveness. J Pharmacol Exp Ther 1990; 253: 688– 697. 21 Sheu JR, Hung WC, Lee YM, Yen MH. Mechanism of inhibition of platelet aggregation by rutaecarpine, an alkaloid isolated from Evodia rutaecarpa. Eur J Pharmacol 1996; 318: 469– 475. 22 King CL, Kong YC, Wong NS, Yeung HW, Fong HHS, Sankawa U. Uterotonic effect of Evodia rutaecarpa alkaloids. J Natl Products 1980; 43: 577– 582. 23 Wang GJ, Shan J, Pang PKT, Yang MCM, Chou CJ, Chen CF. The vasorelaxing action of rutaecarpine: direct paradoxical effect on intracellular calcium concentration of vascular smooth muscle and endothelial cells. J Pharmacol Exp Ther 1996; 276: 1016– 1021. 24 Tobe A, Egawa M, Hashimoto N. Antianoxic effect of 4-(o-benzylphenoxy)-N-methylbutylamine hydro-chloride (MCI-2016). Nippon Yakurigaku Zasshi-Folia Pharmacol Jap 1983; 81: 421– 429. 25 Schubert J, Brill WA. Antagonism of experimental cyanide toxicity in relation to the in vivo activity of cytochrome oxidase. J Pharmacol Exp Ther 1968; 162: 352– 359. 26 Yamahara J, Yamada T, Kitani J, Naitoh Y, Fujimura H. Antianoxic action and active constituents of Evodiae Fructus. Chem Pharm Bull 1989; 37: 1820– 1822. 27 Sheu JR, Yen MH, Lee YM, Su CH, Huang TF. Triflavin inhibits platelet-induced vasoconstriction in de-endothelialized aorta. Arterioscler Thromb Vase Biol 1997; 17: 3461– 3468. 28 Hass WK, Easton JD, Adams HP, et al. A randomized trial comparing ticlopidine hydrochloride with aspirin for the prevention of stroke in high-risk patients. N Engl J Med 1989; 321: 501– 507. 29 Sheu JR, Chao SH, Yen MH, Huang TF. In vivo antithrombotic effect of triflavin, an Arg-Gly-Asp containing peptide on platelet plug formation in mesenteric microvessels of mice. Thromb Haemost 1994; 72: 617– 621. 30 Sato M, Ohshima N. Hemodynamics at stenosis formed by growing platelet thrombi in mesenteric micro-vasculature of rat. Microvasc Res 1986; 31: 66– 76. 31 Nordoy A, Chandler AB. Platelet thrombosis induced by adenosine diphosphate in the rat. Scand J Haematol 1964; 1: 16– 25. 32 Ko HC, Tsai TH, Chou CJ, Hsu SY, Li SY, Chen CF. High-performance liquid chromatographic determination of rutaecarpine in rat plasma: application to a pharmacokinetic study. J Chromatogr 1994; 655: 27– 31. Citing Literature Volume17, Issue3September 1999Pages 237-245 ReferencesRelatedInformation