Revisão Acesso aberto Revisado por pares

Drug-induced Acute Liver Failure

2013; Elsevier BV; Volume: 17; Issue: 4 Linguagem: Inglês

10.1016/j.cld.2013.07.001

ISSN

1557-8224

Autores

William M. Lee,

Tópico(s)

Poisoning and overdose treatments

Resumo

Although acute liver failure caused by drug-induced liver injury comprises a small fraction of overall drug-induced liver injury, these patients require high resource use and have relatively poor outcomes. Drug-induced liver injury caused by idiosyncrasy more often leads to death or transplantation than does acetaminophen acute liver failure, but the number of patients in each category receiving a graft is roughly the same. Efforts in the future to improve outcomes should focus on more effective treatments and better methods to identify those that might experience poor outcomes.

Referência(s)