Studies on aminoazoles: Synthesis of Pyrazolo[1,5‐a]‐pyrimidines and their aza derivatives

1989; Wiley; Volume: 331; Issue: 3 Linguagem: Inglês

10.1002/prac.19893310318

ISSN

0021-8383

Autores

Galal H. Elgemeie, Ahmed H. Elghandour, Hamdy M. Elshimy,

Tópico(s)

Synthesis of heterocyclic compounds

Resumo

Abstract The reaction of 4‐arylazo‐3‐aminopyrazol‐5‐ones ( 1a – i ) with α,β‐unsaturated nitriles, active methylene reagents and nitrile imines are reported. They lead to new polyfunctional derivatives of pyrazolo[1,5‐a]pyrimidine ( 5a – c , 6 , 10a – i , 13a – c , 14a – c , 17a – d , 15 ), pyrazolo‐[5,1‐c]‐1,2,4‐triazine ( 22a – i ) and pyrazolo[5,1‐c]‐1,2,4‐triazole ( 25a – c ). The structures of these products and the mechanisms of their formation are reported.

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