Artigo Acesso aberto Revisado por pares

Diagnosis of medullary thyroid cancer and prognostic factors of disease aggressiveness

2013; VIDAR-M LLC; Volume: ; Issue: 4 Linguagem: Inglês

10.14341/serg201344-13

ISSN

2310-3965

Autores

Д О Газизова, D. G. Beltsevich, Anatoliy Tiulpakov, Т В Солдатова, А V Ilyin,

Tópico(s)

Biomarkers in Disease Mechanisms

Resumo

In the study were enrolled 137 patients with medullary thyroid cancer (MTC). Low 35%-sensitivity of FNAC and high accuracy of basal calcitonin in MTC diagnostics were found. Mutation analysis of the RET pro- tooncogene in familial and sporadic MTC, RAS -gene in sporadic MTC were done. The correlation between type of the mutation and disease aggressiveness was found.

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