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C. elegans RNAi space experiment (CERISE) in Japanese Experiment Module KIBO

2009; Volume: 23; Issue: 4 Linguagem: Inglês

10.2187/bss.23.183

1349-967X

Atsushi Higashitani, Tōkō Hashizume, Tomoko Sugimoto, Chihiro Mori, Kanako Nemoto, Timothy Etheridge, Nahoko Higashitani, Takako Takanami, Hiromi Suzuki, Keiji Fukui, Takashi Yamazaki, Noriaki Ishioka, Nathaniel J. Szewczyk, Akira Higashibata,

Light effects on plants

We have started a space experiment using an experimental organism, the nematode Caenorhabditis elegans, in the Japanese Experiment Module, KIBO, of the International Space Station (ISS). The specimens were boarded by space shuttle Atlantis on mission STS-129 which launched from NASA Kennedy Space Center on November 16, 2009. The purpose of the experiment was several-fold: (i) to verify the efficacy of RNA interference (RNAi) in space, (ii) to monitor transcriptional and post-translational alterations in the entire genome in space, and (iii) to investigate mechanisms regulating and countermeasures for muscle alterations in response to the space environment. In particular, this will be the first study to utilize RNAi in space.