Effects of L-tryptophan on short term food intake in lean men
1985; Elsevier BV; Volume: 5; Issue: 6 Linguagem: Inglês
10.1016/s0271-5317(85)80240-2
ISSN1879-0739
AutoresNina Hrboticky, Lawrence A. Leiter, G. Harvey Anderson,
Tópico(s)Diet and metabolism studies
ResumoThe effects of 1-tryptophan (TRP) on energy and macronutrient consumption were investigated in two experiments. After a standardized breakfast (8:30 a.m.) healthy young men of ±10% ideal body weight took capsulated TRP or lactose placebo (PL), 45 minutes prior to a buffet-type luncheon (12:00 noon). In the first study of 17 subjects, energy intake was reduced by 2 g TRP (1516±96 kcal, ±SEM) compared to PL (1743±84 kcal), p<0.001. In the second study, 3 levels of TRP (1, 2 and 3 g) were tested in 15 subjects. Energy intake was reduced with 2 g TRP (1246±53 kcal) and with 3 g TRP (1236±101 kcal) but not with 1 g TRP (1457±62 kcal) when compared to PL (1541 ±73 kcal), p<0.001. TRP did not have a statistically significant effect on the proportion of carbohydrate or protein energy selected but did cause a selective decrease in consumption of dinner rolls and cookies. Two and 3 g TRP also induced several psychotropic changes including decreased subjective hunger and alertness, with increased faintness and dizziness. We conclude that TRP at or above 2 g decreases short term food intake in lean men.
Referência(s)