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Highly Efficient Synthesis of UDP‐GalNAc/GlcNAc Analogues with Promiscuous Recombinant Human UDP‐GalNAc Pyrophosphorylase AGX1

2010; Wiley; Volume: 16; Issue: 45 Linguagem: Inglês

10.1002/chem.201002315

1521-3765

Wanyi Guan, Li Cai, Peng George Wang,

Lysosomal Storage Disorders Research

Glycodiversification: We describe a highly efficient and preparative synthesis of UDP-GalNAc/GlcNAc and their analogues with promiscuous recombinant human UDP-GalNAc pyrophosphorylase on a preparative scale with good yields (see scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.