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Effect of Garcinia cambogia extract on serum leptin and insulin in mice

2003; Elsevier BV; Volume: 74; Issue: 3 Linguagem: Inglês

10.1016/s0367-326x(03)00036-4

1873-6971

Kohsuke Hayamizu, H Hirakawa, Daichi Oikawa, T. Nakanishi, Tsutomu Takagi, Takashi Tachibana, Mitsuhiro Furuse,

Sleep and Wakefulness Research

In this study we examined the effects of 3.3% Garcinia cambogia extract on 10% sucrose loading in mice for 4 weeks. Treatment was found to have no effect on body weight, fat pad weight or serum glucose level. On the other hand, serum total cholesterol, triglycerides, NEFA were observed. Levels of serum insulin and leptin, as well as the leptin/WAT ratio, were lower in the treated mice than in the control. These findings suggested that G. cambogia extract efficiently improved glucose metabolism and displayed leptin-like activity.