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Acute Porphyria with Unusual Features

1951; BMJ; Volume: 1; Issue: 4717 Linguagem: Inglês

10.1136/bmj.1.4717.1240

0959-8138

E. Grossfeld,

Neonatal Health and Biochemistry

100 ml.Of the 12 cases above this figure, one was complicated by amyloid disease, while another was a diabetic with a glucose level in the pleural effusion of 220 mg./ 100 ml.A glucose level of under 60 mg./ 100 ml.would there- fore appear to be strongly suggestive of the tuberculous origin of a serous pleural effusion.Where the glucose level is over 100 mg./100 ml. the effusion is probably of non-tuberculous origin.The six " undiagnosed " cases had glucose levels ranging from 62 to 96 mg./ 100 ml.Four of these six cases were considered clinically and radiologically to be of tuberculous post-primary type, but bacteriological confirmation was lacking.The four patients were adolescents or young adults, with straw-coloured lymphocytic effusions of recent onset, and gave positive Mantoux reactions.There were eight tuberculous patients with glucose levels between 60 and 100 mg./ 100 ml. and seven non- tuberculous.The glucose values in the six " undiag- nosed" cases would therefore be of no value in deciding the aetiology of the effusion. SummaryThe pleural glucose level has been studied in 61 cases of serous effusion.In these cases: (a) a glucose level of less than 60 mg./ 100 ml. was found only in tuberculous effusions; (b) the majority of tuberculous effusions had glucose levels of less than 100 mg./100 ml., while most non-tuberculous effusions had levels above 100 mg./ 100 ml.; and (c) no significance could be attached to glucose levels of between 60 and 100 mg./100 ml.