Produção Nacional
Revisado por pares
Effects of Urinary Tract Infection in Patients With Bladder Augmentation and Kidney Transplantation
2008; Lippincott Williams & Wilkins; Volume: 180; Issue: 6 Linguagem: Inglês
10.1016/j.juro.2008.08.049
ISSN1527-3792
AutoresDaniel Alcântara Pereira, Ubirajara Barroso, P.G.P Machado, José Osmar Medina Pestana, Thiago Elias Rosito, Jesus Pires, Cláudio Almeida, Valdemar Ortiz, António Macedo,
Tópico(s)Pelvic floor disorders treatments
ResumoNo AccessJournal of UrologyPediatric Urology1 Dec 2008Effects of Urinary Tract Infection in Patients With Bladder Augmentation and Kidney Transplantation Daniel Alcântara Pereira, Ubirajara Barroso, Paula Machado, José Osmar Medina Pestana, Thiago Elias Rosito, Jesus Pires, Cláudio Almeida, Valdemar Ortiz, and Antonio Macedo Daniel Alcântara PereiraDaniel Alcântara Pereira More articles by this author , Ubirajara BarrosoUbirajara Barroso More articles by this author , Paula MachadoPaula Machado More articles by this author , José Osmar Medina PestanaJosé Osmar Medina Pestana More articles by this author , Thiago Elias RositoThiago Elias Rosito More articles by this author , Jesus PiresJesus Pires More articles by this author , Cláudio AlmeidaCláudio Almeida More articles by this author , Valdemar OrtizValdemar Ortiz More articles by this author , and Antonio MacedoAntonio Macedo More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2008.08.049AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We evaluated the rate of function decline of the renal allograft in patients with augmented bladder. We also evaluated the prevalence of asymptomatic bacteriuria and urinary tract infection in these patients, and to demonstrate if these findings are predictors of allograft function decline, comparing children who underwent bladder augmentation with a control group. Materials and Methods: Among 170 children and adolescents undergoing renal transplantation at our institution 23 (14%) had previously undergone bladder augmentation. These patients were retrospectively compared (1:2 ratio) to 42 controls matched for gender, age, race, donor type, weight and immunosuppression protocol. The type of donor (living or cadaver), rate of acute tubular necrosis and cold ischemia time during transplantation were also similar between groups. Results: Mean followup was 18.0 ± 13.9 months and 25.2 ± 14.1 months for the augmented and nonaugmented bladder groups, respectively (p >0.05). The incidence of acute rejection within the first 12 months of kidney transplantation was 9% in the bladder augmentation group and 26% in controls (p >0.05). The rate of urinary tract infection or asymptomatic bacteriuria in the first 12 months after kidney transplantation was higher in the bladder augmentation group (19 patients, 83%) compared to controls (7 patients, 17%, p <0.001). Patients with augmented bladder had a higher number of hospital admissions (14 patients, 61%) compared to the control group (12 patients, 29%, p = 0.004). Despite the higher incidence of urinary tract infection in the augmented bladder group, there was no statistically significant difference in graft function between the groups at 6 months (1.1 ± 0.3 mg/dl vs 1.0 ± 0.3 mg/dl) or 12 months (1.0 ± 0.2 mg/dl vs 1.2 ± 0.7 mg/dl) after transplantation. Conclusions: Our study demonstrated that patients with transplanted kidney and augmented bladder had more asymptomatic bacteriuria and urinary tract infections than those without bladder augmentation. However, the rate of graft survival was similar between the groups. References 1 : Fate of renal allografts transplanted in patients with urinary diversion. Transplantation1993; 56: 838. Crossref, Medline, Google Scholar 2 : Renal transplantation in children with augmentation cystoplasty: long-term results. J Urol1998; 159: 2110. Link, Google Scholar 3 : Clinical and urodynamic evaluation after ureterocystoplasty and kidney transplantation. J Urol2004; 171: 1428. Link, Google Scholar 4 : Renal transplantation in children with severe lower urinary tract dysfunction. J Urol1999; 161: 240. Link, Google Scholar 5 : Renal transplantation following renal failure due to urological disorders. Nephrol Dial Transplant1998; 13: 2065. 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Volume 180Issue 6December 2008Page: 2607-2610 Advertisement Copyright & Permissions© 2008 by American Urological AssociationKeywordsurinary tract infectionsurinary bladder, neurogenickidney transplantationchildMetricsAuthor Information Daniel Alcântara Pereira More articles by this author Ubirajara Barroso More articles by this author Paula Machado More articles by this author José Osmar Medina Pestana More articles by this author Thiago Elias Rosito More articles by this author Jesus Pires More articles by this author Cláudio Almeida More articles by this author Valdemar Ortiz More articles by this author Antonio Macedo More articles by this author Expand All Advertisement PDF downloadLoading ...
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