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A Cineangiocardiographic Study of the Regional Contraction Sequence of the Normal and Diseased Left Ventricle in Man

1969; Japanese Heart Journal Assoc; Volume: 10; Issue: 2 Linguagem: Inglês

10.1536/ihj.10.95

1573-8612

Hideo UEDA, Keiji Ueda, Shigenori Morooka, Atsuo NAKANISHI, Iwao Ito, Hisakazu Yasuda, Yutaka Takabatake, Yasuro Sugishita, Yasumi Uchida, Katsuhiko Ozeki,

Magnetic Properties and Applications

The regional contraction sequence of the left ventricle (LV) was analyzed by 16mm. cineangiocardiograms (in LAO, 40 frames per sec.) of 5 control subjects, 4 patients with mitral insufficiency, 2 with idiopathic hypertrophic subaortic stenosis (IHSS), 2 with idiopathic myocardial hypertrophy and 3 of myocardial disease with LV dilatation.The LV cavity was divided into basal, middle and apical portion, and internal width (diameter) for each portion was measured on a line drawn perpendicular to the long axis at 3 equally spaced points. The time course of the length of the diameters in percentage of the initial length was compared, and circumferential shortening velocity (Vcs) and total extent of circumferential shortening were calculated for each diameter. Regional contraction sequence was also analyzed by superimpositon of serial LV silhouettes during systole.In control subjects, a synchronized contraction sequence was suggested, and regional circumferential shortening velocity was inversely related to the initial length of corresponding diameter. In hypertrophied and dilated hearts of mitral insufficiency or in IHSS, an earlier onset and/or more rapid contraction of the basal portion were noted. The possible relationship between asynchronism of the contraction sequence and alterations of ventricular geometry and of myocardial architecture of the LV were discussed. In myocardial disease with dilated LV, both shortening velocity and extent of shortening were markedly reduced.The method described here allows direct observation of the pattern of regional contraction sequence and also gives clinical indices of contractile state of the myocardium in normal and diseased LV in man.