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The Association of Progressive Systemic Sclerosis (Scleroderma) with Coal Miners' Pneumoconiosis and Other Forms of Silicosis

1967; American College of Physicians; Volume: 66; Issue: 2 Linguagem: Inglês

10.7326/0003-4819-66-2-323

1539-3704

Gerald P. Rodnan,

Inflammatory Myopathies and Dermatomyositis

Article1 February 1967The Association of Progressive Systemic Sclerosis (Scleroderma) with Coal Miners' Pneumoconiosis and Other Forms of SilicosisGERALD P. RODNAN, M.D., F.A.C.P., THOMAS G. BENEDEK, M.D., THOMAS A. MEDSGER JR., M.D., ROY J. CAMMARATA, M.D.GERALD P. RODNAN, M.D., F.A.C.P., THOMAS G. BENEDEK, M.D., THOMAS A. MEDSGER JR., M.D., ROY J. CAMMARATA, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-66-2-323 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptProgressive systemic sclerosis (PSS or scleroderma) occurs in men engaged in many kinds of work, and until recently there has been little reason to suspect that this disease might be preferentially associated with any particular occupation. In 1957, however, Erasmus (1) presented an account of 17 cases of scleroderma in underground gold miners on the Witwatersrand in South Africa and drew attention to an earlier report of scleroderma among Scottish stonemasons by Bramwell (2). Erasmus was impressed not only by the prevalence of the disease among the miners (all but one of whom were Europeans) but also by certain clinical...References1. ERASMUS LD: Scleroderma in gold-miners on the Witwatersrand with particular reference to pulmonary manifestations. S. Afr. J. Lab. Clin. Med. 3: 209, 1957. MedlineGoogle Scholar2. BRAMWELL B: Diffuse sclerodermia: its frequency; its occurrence in stone-masons; its treatment by fibrolysin-elevations of temperature due to fibrolysin injections. Edinburgh Med. J. 12: 387, 1914. Google Scholar3. BONARD EC: Le poumon dans la sclérodermie. Schweiz. Med. Wschr. 88: 373, 1958. MedlineGoogle Scholar4. TRAISSACFONTANILLE FP: Silicose pulmonaire et dermo-ostéopathies. J. Med. Bordeaux 135: 829, 1958. 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TUFFANELLIWINKELMANN DLRK: Systemic scleroderma. A clinical study of 727 cases. Arch. Derm. (Chicago) 84: 359, 1961. CrossrefMedlineGoogle Scholar27. RIVELIS AL: Progressive systemic sclerosis. A report on 66 cases. AIR 6: 517, 1963. Google Scholar28. CAPLAN A: Certain unusual radiological appearances in the chest of coal miners suffering from rheumatoid arthritis. Thorax 8: 29, 1953. CrossrefMedlineGoogle Scholar29. CAPLANPAYNEWITHEY ARBJL: A broader concept of Caplan's syndrome related to rheumatoid factors. Thorax 17: 205, 1962. CrossrefMedlineGoogle Scholar30. GOUGHRIVERSSEAL JDRM: Pathologic studies of modified pneumoconiosis in coal miners with rheumatoid arthritis (Caplan's syndrome). Thorax 10: 9, 1955. CrossrefMedlineGoogle Scholar31. VIGLIANIPERNIS ECB: Immunological aspects of silicosis. Advances Tuberc. Res. 12: 230, 1963. Google Scholar32. SPENCER H: Pathology of the Lung. The Macmillan Co., New York, 1962. Google Scholar33. COLLINSDARKEDODGE DHCSOG: Scleroderma with honeycomb lungs and bronchiolar carcinoma. J. Path. Bact. 76: 531, 1958. CrossrefMedlineGoogle Scholar34. CAPLAN H: Honeycomb lungs and malignant pulmonary adenomatosis in scleroderma. Thorax 14: 89, 1959. CrossrefMedlineGoogle Scholar35. DIXONBALL ASJ: Honeycomb lung and chronic rheumatoid arthritis. A case report. Ann. Rheum. Dis. 16: 241, 1957. CrossrefMedlineGoogle Scholar36. RODNAN GP: A review of recent observations and current theories on the etiology and pathogenesis of progressive systemic sclerosis (diffuse scleroderma). J. Chronic Dis. 16: 929, 1963. CrossrefMedlineGoogle Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAuthors: GERALD P. RODNAN, M.D., F.A.C.P.; THOMAS G. BENEDEK, M.D.; THOMAS A. MEDSGERJR., M.D.; ROY J. CAMMARATA, M.D.Affiliations: Pittsburgh, PennsylvaniaFrom the Department of Medicine, University of Pittsburgh, the Presbyterian-University Hospital, and the Pittsburgh Veterans Administration Hospital.This study was supported by graduate training grant 2A-5031 in Arthritis and Rheumatism and grant 5 MO1 FR 00056, U. S. Public Health Service, Washington, D. C., and the Western Pennsylvania Chapter of the Arthritis Foundation.Requests for reprints should be addressed to Gerald P. Rodnan, M.D., Department of Medicine, 985 Scaife Hall, University of Pittsburgh, Pittsburgh, Pa. 15213. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byThoracic lymphadenopathies in diffuse systemic sclerosis: an observational study on 48 patients using computed tomographyEnvironmental Risks for Systemic SclerosisNosografía de las dermatosis profesionalesSystemic SclerosisSclérodermie et exposition professionnelle aux solvants organiques. 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D'ANGELO, M.D. 1 February 1967Volume 66, Issue 2Page: 323-334KeywordsArthritisGraduate medical educationHospital medicineMedical servicesPathogenesisPneumoconiosesSclerodermaSilicosisSystemic diseases ePublished: 1 December 2008 Issue Published: 1 February 1967 PDF downloadLoading ...