Benzodiazepines as appetite-enhancing compounds
1980; Elsevier BV; Volume: 1; Issue: 1 Linguagem: Inglês
10.1016/s0195-6663(80)80005-5
ISSN1095-8304
Autores Tópico(s)Child Nutrition and Feeding Issues
ResumoThere is consistent evidence that benzodiazepines may enhance appetite for food by relatively direct means. However, the evidence that they overcome food neophobia, and thereby increase food intake as a secondary effect, fails to be conclusive. Recent food selection studies nevertheless point to two dissociable actions of the drugs. At lower dose levels, benzodiazepines may act relatively selectively to mimic the effects of increased hunger. At higher dose levels, however, they display effects which are consistent with an action to reduce food neophobia. These behavioural studies indicate that appetitive effects of benzodiazepines are distinguishable from their anxiolytic effects. Clinically, this may point to an effective use of benzodiazepines in the treatment of feeding disorders.
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