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Generalized Ostraceous Psoriasis

2010; Massachusetts Medical Society; Volume: 362; Issue: 2 Linguagem: Inglês

10.1056/nejmicm0810475

1533-4406

Salvador Arias‐Santiago, Ramón Naranjo‐Sintes,

Autoimmune Bullous Skin Diseases

A 47-year-old woman presented to our hospital with a 2-week history of widespread, painful lesions on her trunk and limbs (Panels A and B). Her medical history included hypercholesterolemia, diabetes, and a 10-year history of psoriasis that had been treated with corticosteroids, calcipotriene, and methotrexate. Five months before presentation, the patient's psoriasis went into remission, and treatment was discontinued. Physical examination revealed sharply demarcated, erythematous, well-defined limpetlike plaques covered with scales and crust. Laboratory testing revealed hyperglycemia and hypercholesterolemia. A diagnosis of ostraceous psoriasis was made. The patient was treated with topical petrolatum containing 20% salicylic acid and mometasone furoate . . .