Iodine-catalyzed efficient synthesis of chalcones by grinding under solvent-free conditions
2009; NRC Research Press; Volume: 87; Issue: 9 Linguagem: Inglês
10.1139/v09-106
ISSN1480-3291
Autores Tópico(s)Synthesis and Biological Evaluation
ResumoChalcones are useful intermediates in organic synthesis and exhibit a large number of different biological activities. Chalcones have been synthesized in high yields by Claisen–Schmidt condensation of substituted acetophenones with various aromatic aldehydes in the presence of 10 mol% of iodine at room temperature by grinding under solvent-free conditions.
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