A study of chemical carcinogenesis 4. Synthesis of the carbon‐14 labelled carcinogens 5‐methylchrysene, 2‐methyl‐aniline and 3‐methyl‐2‐naphthylamine
1978; Wiley; Volume: 14; Issue: 1 Linguagem: Inglês
10.1002/jlcr.2580140116
ISSN1099-1344
AutoresLouis M. Weiss, Myrna Loy, Stephen S. Hecht, Dietrich Hoffmann,
Tópico(s)Chemical Reactions and Isotopes
ResumoAbstract Procedures were developed for synthesis of the carcinogenic compounds 5‐methylchrysene‐5‐ 14 C, 2‐methylaniline‐methyl‐ 14 C and 3‐methyl‐2‐naphthyl‐amine‐methyl‐ 14 C. In each case, label was introduced with 14 CO 2 and yields were acceptable for preparation of these compounds for metabolic studies.
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