Mild cognitive impairment
2003; Lippincott Williams & Wilkins; Volume: 60; Issue: 8 Linguagem: Inglês
10.1212/01.wnl.0000055847.17752.e6
ISSN1526-632X
AutoresGaël Chételat, Béatrice Desgranges, Vincent de La Sayette, Fausto Viader, Francis Eustache, Jean‐Claude Baron,
Tópico(s)Diet and metabolism studies
ResumoPatients with mild cognitive impairment (MCI) were assessed, and a metabolic profile associated with conversion to AD at 18-month follow-up was sought. As compared with nonconverters (n = 10), converters (n = 7) had lower fluorodeoxyglucose uptake in the right temporoparietal cortex ( p = 0.02, corrected for cluster size), without individual overlap. Awaiting replication in an independent sample, these findings suggest that among patients with MCI, fluorodeoxyglucose PET may accurately identify rapid converters.
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