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Peptidomimetics derived from natural products

1993; Wiley; Volume: 13; Issue: 3 Linguagem: Inglês

10.1002/med.2610130305

1098-1128

Robert A. Wiley, Daniel H. Rich,

Peptidase Inhibition and Analysis

Medicinal Research ReviewsVolume 13, Issue 3 p. 327-384 Article Peptidomimetics derived from natural products Robert A. Wiley, Robert A. Wiley College of Pharmacy, The University of Iowa, Iowa City, Iowa 52242 Robert A. Wiley: was educated in Pharmacy at the University of Michigan and in medicinal chemistry at the University of California-San Francisco, where he worked with Eugene Jorgensen. He joined Ed Smissman's medicinal chemistry group at the University of Kansas in 1962 and served there until 1984. His research interests focused on organophosphorus compounds, phospholipid mediators of cardiovascular function, and metabolic mechanisms of tissue injury produced by organic chemicals. He served as Dean of the College of Pharmacy at the University of Iowa from 1984 until 1991, and is currently a Professor of Medicinal Chemistry there.Search for more papers by this authorDaniel H. Rich Dr., Corresponding Author Daniel H. Rich Dr. School of Pharmacy and Department of Chemistry, The University of Wisconsin—Madison, Madison, Wisconsin 53706 Dr. Daniel H. Rich received the B. Chem degree in chemistry from the University of Minnesota in 1964 and his Ph.D. degree in organic chemistry under A. T. Blomquist at Cornell University in 1968. He held postdoctoral positions at Cornell, Dow Chemical Co., and Stanford University (with W. S. Johnson) before joining the Faculty of the School of Pharmacy at the University of Wisconsin-Madison in 1970. Dr. Rich is now Professor of Medicinal Chemistry in the School of Pharmacy and Professor of Chemistry in the Department of Chemistry. His research has focused on the synthesis and conformational analysis of cyclic peptides and the design and synthesis of inhibitors of therapeutically important enzymes, especially aspartic proteases and peptidyl prolyl isomerases.The University of Wisconsin-Madison, 2320 Chamberlin Hall, 425 N. Charter St., Madison, WI 53706Search for more papers by this author Robert A. Wiley, Robert A. Wiley College of Pharmacy, The University of Iowa, Iowa City, Iowa 52242 Robert A. Wiley: was educated in Pharmacy at the University of Michigan and in medicinal chemistry at the University of California-San Francisco, where he worked with Eugene Jorgensen. He joined Ed Smissman's medicinal chemistry group at the University of Kansas in 1962 and served there until 1984. His research interests focused on organophosphorus compounds, phospholipid mediators of cardiovascular function, and metabolic mechanisms of tissue injury produced by organic chemicals. He served as Dean of the College of Pharmacy at the University of Iowa from 1984 until 1991, and is currently a Professor of Medicinal Chemistry there.Search for more papers by this authorDaniel H. Rich Dr., Corresponding Author Daniel H. Rich Dr. School of Pharmacy and Department of Chemistry, The University of Wisconsin—Madison, Madison, Wisconsin 53706 Dr. Daniel H. Rich received the B. Chem degree in chemistry from the University of Minnesota in 1964 and his Ph.D. degree in organic chemistry under A. T. Blomquist at Cornell University in 1968. He held postdoctoral positions at Cornell, Dow Chemical Co., and Stanford University (with W. S. Johnson) before joining the Faculty of the School of Pharmacy at the University of Wisconsin-Madison in 1970. Dr. Rich is now Professor of Medicinal Chemistry in the School of Pharmacy and Professor of Chemistry in the Department of Chemistry. His research has focused on the synthesis and conformational analysis of cyclic peptides and the design and synthesis of inhibitors of therapeutically important enzymes, especially aspartic proteases and peptidyl prolyl isomerases.The University of Wisconsin-Madison, 2320 Chamberlin Hall, 425 N. Charter St., Madison, WI 53706Search for more papers by this author First published: May 1993 https://doi.org/10.1002/med.2610130305Citations: 185 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Citing Literature Volume13, Issue3May 1993Pages 327-384 RelatedInformation