Revisão Acesso aberto Revisado por pares

The systemic inflammatory response syndrome

2006; Elsevier BV; Volume: 8; Issue: 5 Linguagem: Inglês

10.1016/j.micinf.2005.12.016

ISSN

1769-714X

Autores

Charles M. Robertson, Craig M. Coopersmith,

Tópico(s)

Immune Response and Inflammation

Resumo

The systemic inflammatory response syndrome (SIRS) is the body's response to an infectious or noninfectious insult. Although the definition of SIRS refers to it as an "inflammatory" response, it actually has pro- and anti-inflammatory components. This review outlines the pathophysiology of SIRS and highlights potential targets for future therapeutic intervention in patients with this complex entity.

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