Artigo Acesso aberto Revisado por pares

Signs of Inflammation After Sciatic Nerve Block in Pigs

2005; Lippincott Williams & Wilkins; Linguagem: Inglês

10.1213/01.ane.0000184255.43746.89

ISSN

1526-7598

Autores

Wolfgang Voelckel, Günther Klima, Anette C. Krismer, Christopher Haslinger, Karl H. Stadlbauer, Volker Wenzel, Achim von Goedecke,

Tópico(s)

Spine and Intervertebral Disc Pathology

Resumo

Nerve stimulators are widely used to assist with peripheral nerve blocks but do not eliminate the risk of nerve injury. We evaluated the histologic findings 6 h after sciatic nerve block with bupivacaine in pigs. When a motor response was still obtained with a current <0.2 mA (n = 10), the postmortem microscopic evaluation revealed lymphocytes and granulocytes sub-, peri-, and intraneurally in 5 (50%) of 10 pigs. No signs of inflammation were observed when the muscle contraction was achieved with a current between 0.3 and 0.5 mA (P = 0.03). In conclusion, the current required to elicit a motor response, the position of the needle tip, and the subsequent likelihood of nerve damage merit further evaluation.

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