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Acute renal failure after massive honeybee stings

2003; UNIVERSIDADE DE SÃO PAULO; Volume: 45; Issue: 1 Linguagem: Inglês

10.1590/s0036-46652003000100010

1678-9946

Elizabeth De Francesco Daher, Geraldo Bezerra da Silva, Glaydcianne Pinheiro Bezerra, Lícia Borges Pontes, Alice Maria Costa Martins, Jorge A. Guimarães,

Venomous Animal Envenomation and Studies

Two clinical cases of patients who survived after numerous attacks of Africanized bees (600 and 1500 bee stings, respectively) are reported. Clinical manifestation was characterized by diffuse and widespread edema, a burning sensation in the skin, headache, weakness, dizziness, generalized paresthesia, somnolence and hypotension. Acute renal failure developed and was attributed to hypotension, intravascular hemolysis, myoglobinuria due to rhabdomyolysis and probably to direct toxic effect of the massive quantity of injected venom. They were treated with antihistaminic, corticosteroids and fluid infusion. One of them had severe acute renal failure and dialysis was required. No clinical complication was observed during hospital stay and complete renal function recovery was observed in both patients. In conclusion, acute renal failure after bee stings is probably due to pigment nephropathy associated with hypovolemia. Early recognition of this syndrome is crucial to the successful management of these patients.