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CORTICAL AND SUBCORTICAL SEIZURE DISCHARGE INDUCED BY BITEMPORAL ELECTROSHOCK IN CAT

1959; Wiley; Volume: 13; Issue: 2 Linguagem: Inglês

10.1111/j.1440-1819.1959.tb02426.x

1440-1819

Matué Miyasaka,

Neuroscience and Neural Engineering

SUMMARY Bitemporal and bifrontal electroshock (AC.50 cps., threshold voltage, 2 sec.) was applied to twenty five curarized cats, and the pattern of the induced seizure discharge and their regional correlation were studied in the neo‐, paleo‐ (amygdala), archicortex (hippocampus) and subcortical structures. No essential difference of the seizure activity was seen between both electroshock procedures. The seizure activity has tendency to originate in the neocortex (especially in the sensorimotor cortex), and also in the archicortex, but not in the subcortical structures. The seizure discharge in phylogenetically different three cortices often reveals a clear dissociation in the initiation, spreading and termination, together with difference in frequency and voltage. The seizure discharge in the subcortical structures shows closely related activities to the functionally intimate cortex: thalamus and caudate to neocortex; anterior part of hypothalamus and globus pallidus to paleocortex (amygdala); posterior part of hypothalamus and septal region to archicortex (hippocampus). The most important role of the hippocampus in electroshock treatment was discussed.