Eosinophilic Granuloma in the Pediatric Spine
2007; Karger Publishers; Volume: 43; Issue: 4 Linguagem: Inglês
10.1159/000103308
ISSN1423-0305
AutoresJeremy D.W. Greenlee, Albert J. Fenoy, Kathleen A. Donovan, Arnold H. Menezes,
Tópico(s)Spinal Dysraphism and Malformations
Resumo<i>Background/Aims:</i> Eosinophilic granuloma (EG) involving the vertebrae in the pediatric population presents a difficult management scenario. Issues of surgical versus nonsurgical intervention, spinal stability and continued skeletal growth must all be considered. <i>Methods:</i> A retrospective review of medical records and radiographs from 1964 to the present yielded 12 patients with age less than 18 at the time of diagnosis of primary spinal EG. <i>Results:</i> Eleven of these 12 patients presented with pain; 2 patients had neurological deficits. Nine patients were managed nonsurgically, including those undergoing tissue diagnosis by needle (2) or extraspinal (3) biopsy; 3 patients underwent gross total resections. Radiographic diagnosis alone was made in 4. With an average follow-up of 8.1 years, survival is 100%. <i>Conclusions:</i> EG in the spine infrequently produces neurological deficits in the pediatric age group, although it may result in spinal instability. As such, nonsurgical management is the preferred strategy to effect symptomatic relief.
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