Portal de Periódicos da CAPES

Acanthosis Nigricans and Autoimmune Reactivity

1981; American Medical Association; Volume: 246; Issue: 7 Linguagem: Inglês

10.1001/jama.1981.03320070047024

1538-3598

Raymond A. Sturner, Stephen Denning, Patricia Marchase,

Cardiovascular Effects of Exercise

Acanthosis nigricans has been associated with malignant diseases and endocrinopathy. One of the cases reported herein and a review of 12 others suggest that the onset of acanthosis nigricans may predate a variety of classic autoimmune diseases. The other case being reported now, along with a literature review of 22 cases, suggests that acanthosis nigricans also may be associated with disordered immunoreactivity not fitting any clinically recognizable syndrome. ( JAMA 1981;246:763-765)