Total Synthesis of (±)-Dictamnol by a Free Radical Fragmentation/Elimination Sequence. Confirmation of its Revised Structure
1997; Elsevier BV; Volume: 38; Issue: 36 Linguagem: Inglês
10.1016/s0040-4039(97)01466-4
ISSN1873-3581
AutoresGordon L. Lange, Alexandru Merica, Melerin Chimanikire,
Tópico(s)Sesquiterpenes and Asteraceae Studies
ResumoThe trinor-guaiane sesquiterpenoid (±)-dictammol 2 was synthesized, in only 6 steps, from photoadduct 5. The crucial step involved a SmI2-mediated tandem free radical fragmentation/elimination reaction of diiodide 10. Support for the recently revised structure of dictamnol is presented. © 1997 Elsevier Science Ltd.
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