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BIBTEX RIS

A procedure to recruit members to enlarge protein family databases - the building of UECOG (UniRef-Enriched COG Database) as a model

2008; Research Foundation of Ribeirão Preto; Volume: 7; Issue: 3 Linguagem: Inglês

10.4238/vol7-3x-meeting008

ISSN

1676-5680

Autores

Gabriel da Rocha Fernandes, Daniela Barbosa, Francisco Prosdocimi, Izabella A. Pena, Lucas Santana‐Santos, Otávio Augusto Mazzoni Coelho, Adriano Barbosa-Silva, Henrique Velloso, Maurício A. Mudadu, Darren A. Natale, Alessandra Faria-Campos, Sílvio Aguiar, José Miguel Ortega,

Tópico(s)

Genomics and Phylogenetic Studies

Resumo

UniRef-Enriched COG0151 (UECOG) was tested with distinct procedures to compare recruited members with the recruiters: PSI-BLAST, secondary structure overlap (SOV), Seed Linkage, COGnitor, shared domain content, and neighbor-joining single-linkage, and observed that the former four agree in their validations.Presently, the UniRef50-based recruitment procedure enriches the COG database for Archaea, Bacteria and its subgroups Actinobacteria, Firmicutes, Proteobacteria, and other bacteria by 2.2-, 8.0-, 7.0-, 8.8-, 8.7-, and 4.2-fold, respectively, in terms of sequences, and also considerably increased the number of species.

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