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BIBTEX RIS

The significance of Howell-Jolly bodies and giant metamyelocytes in marrow smears

1961; BMJ; Volume: 14; Issue: 4 Linguagem: Inglês

10.1136/jcp.14.4.374

ISSN

1472-4146

Autores

D. W. Dawson, Henry Bury,

Tópico(s)

Erythrocyte Function and Pathophysiology

Resumo

Howell-Jolly bodies in erythroid precursors can be found in the marrow in a variety of diseases. More than 1% in the later erythroblasts is rarely found except in vitamin B(12) or folic acid deficiency states.Giant metamyelocytes are probably always the result of vitamin B(12) or folic acid deficiency. A distinction is drawn between the deficiency of, and therapeutic need for, vitamin B(12) and folic acid.

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