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Antigenic Analysis of Echoviruses 1 and 8

1973; Oxford University Press; Volume: 127; Issue: 1 Linguagem: Inglês

10.1093/infdis/127.1.63

1537-6613

LeRoy F. Harris, Ralph E. Haynes, Henry G. Cramblett, Robert Conant, Gail Jenkins,

Animal Virus Infections Studies

The antigenic relationship between prototype and isolate strains of echovirus types 1 and 8 was confirmed by double-diffusion gel-precipitation studies. All strains shared a common antigen. In addition, some strains possessed a second antigen that related them more closely to one or the other of the prototype strains. The prototype and isolate strains failed to show the classical prime relationship described for echovirus type 6. The antigenic variation is similar to that described for echovirus types 4 and 9. For this reason the diagnostic laboratory should consider the use of antisera to both prototype and variant strains.