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Increased incidence of infection in verapamil-treated kidney transplant recipients

2000; Elsevier BV; Volume: 32; Issue: 3 Linguagem: Inglês

10.1016/s0041-1345(00)00886-1

1873-2623

G Nanni, Nicola Panocchia, Roberto M. Tacchino, M Foco, Elisabetta Piccioni, M Castagneto,

Nausea and vomiting management

This chapter discusses several β-adrenoceptor antagonists and antianginal drugs.Propranolol and gabapentin are both effective in essential tremor. Gabapentin can occasionally cause reversible movement disorders. Concurrent systemic β-blocker therapy had no deleterious effects on ocular hypotensive efficacy and no impact on safety with topical brimonidine, but the combination of timolol and brimonidine significantly reduced systolic and diastolic blood pressures and heart rate compared with brimonidine alone. Surgery is the standard treatment of anal fissures, the most common and painful anal disease. Local application of glyceryl trinitrate improves symptoms by relaxing the internal anal sphincter. In a multicenter, randomized, placebo-controlled, doubleblind study of 0.2% glyceryl trinitrate ointment in 132 patients over at least 4 weeks healing rates were similar with glyceryl trinitrate and placebo, but adverse events were more frequent in those who used glyceryl trinitrate. Isosorbide-5-mononitrate added to propranolol appeared to be less well tolerated than propranolol alone, because seven patients had to be withdrawn from treatment because of adverse effects (four with feelings of faintness, two with headache, one with angina-like chest pain), compared with one with atrioventricular block taking propranolol alone.