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BIBTEX RIS

Aminoacid Sequence of Dogfish M 4 Lactate Dehydrogenase

1973; National Academy of Sciences; Volume: 70; Issue: 6 Linguagem: Inglês

10.1073/pnas.70.6.1790

ISSN

1091-6490

Autores

Susan S. Taylor, Susanna S. Oxley, William S. Allison, Nathan O. Kaplan,

Tópico(s)

Machine Learning in Bioinformatics

Resumo

About 80% of the aminoacid sequence of dogfish ( Squalus acanthius ) M 4 lactate dehydrogenase (EC 1.1.1.27) has been elucidated. Several sequence homologies with peptides from pig H 4 and pig M 4 lactate dehydrogenase are identified. Histidine 195 is homologous to the essential histidine residue in pig H 4 lactate dehydrogenase. Similarities in the sequence around the “essential” cysteine residue of lactate dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, and yeast and liver alcohol dehydrogenase are delineated.

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