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Combinatorial Self‐Assembly of Glycan Fragments into Microarrays

2010; Wiley; Volume: 12; Issue: 1 Linguagem: Inglês

10.1002/cbic.201000567

1439-7633

Kuo‐Ting Huang, Katarzyna Górska, Susana Álvarez, Sofía Barluenga, Nicolas Winssinger,

Proteoglycans and glycosaminoglycans research

ChemBioChemVolume 12, Issue 1 p. 56-60 Communication Combinatorial Self-Assembly of Glycan Fragments into Microarrays Kuo-Ting Huang, Kuo-Ting Huang Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorKatarzyna Gorska, Katarzyna Gorska Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorDr. Susana Alvarez, Dr. Susana Alvarez Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorDr. Sofia Barluenga, Dr. Sofia Barluenga Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorProf. Nicolas Winssinger, Corresponding Author Prof. Nicolas Winssinger winssinger@isis.u-strasbg.fr Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this author Kuo-Ting Huang, Kuo-Ting Huang Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorKatarzyna Gorska, Katarzyna Gorska Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorDr. Susana Alvarez, Dr. Susana Alvarez Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorDr. Sofia Barluenga, Dr. Sofia Barluenga Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this authorProf. Nicolas Winssinger, Corresponding Author Prof. Nicolas Winssinger winssinger@isis.u-strasbg.fr Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Institut de Science et Ingénierie Supramoléculaires (ISIS), Université de Strasbourg, CNRS (UMR 7006), 8 allée Gaspard Monge, 67000 Strasbourg (France), Fax: (+33) 3-90245112Search for more papers by this author First published: 08 December 2010 https://doi.org/10.1002/cbic.201000567Citations: 40Read the full textAboutRelatedInformationPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessClose modalShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Graphical Abstract Complex glycan arrays: A general method for preparing thioglycosides from native oligosaccharides and coupling them to peptide nucleic acids (PNAs) is reported. An array of 625 glycans was assembled by hybridization of two PNA-encoded libraries of 25 glycan fragments. The cooperativity of the fragment for carbohydrate binding proteins was validated with lectins of known specificity. Citing Literature Supporting Information Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Filename Description cbic_201000567_sm_miscellaneous_information.pdf1.3 MB miscellaneous_information Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article. Volume12, Issue1January 3, 2011Pages 56-60 RelatedInformation