Sister-chromatid exchanges in lymphocytes of smokers in an experimental study
1984; Elsevier BV; Volume: 138; Issue: 2-3 Linguagem: Inglês
10.1016/0165-1218(84)90044-2
ISSN1878-707X
AutoresKirsti Husgafvel‐Pursiainen, Marja Sorsa, Hilkka Järventaus, Hannu Norppa,
Tópico(s)T-cell and Retrovirus Studies
ResumoThe frequency of sister-chromatid exchanges (SCEs) was studied in peripheral blood lymphocytes of 26 young male smokers and 10 non-smokers who had recently entered military service. The levels of SCEs were examined in 4 consecutive blood samples taken after short experimental periods of smoking only low-tar (LT) or medium-tar (MT) cigarettes. The incidence of SCEs was significantly higher in the the group of smokers than in the group of non-smokers. The SCE levels of the smokers were found to be associated with the personal smoking history; the observed increase in the SCE frequency correlated with the years of smoking measured as cumulative pack years. The difference in type of cigarette did not influence the SCE frequencies.
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