Metofluthrin: A Potent New Synthetic Pyrethroid with High Vapor Activity against Mosquitoes
2004; Oxford University Press; Volume: 68; Issue: 1 Linguagem: Inglês
10.1271/bbb.68.170
ISSN1347-6947
AutoresKazuya Ujihara, Tatsuya Mori, Tomonori Iwasaki, Masayo Sugano, Yoshinori Shono, Noritada Matsuo,
Tópico(s)Insect Pheromone Research and Control
Resumo(1R)-trans-Norchrysanthemic acid fluorobenzyl esters are synthesized and their structure-activity relationships are discussed. These esters show outstanding insecticidal activity against mosquitoes. In particular, the 2,3,5,6-tetrafluoro-4-methoxymethylbenzyl analog (metofluthrin) exhibits the highest potency, being approximately forty times as potent as d-allethrin in a mosquito coil formulation when tested against southern house mosquitoes (Culex quinquefasciatus). Metofluthrin also exhibits a significant vapor action at room temperature.
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