In vitro effects of melatonin on HCG stimulation of steroid accumulation by rabbit ovarian follicles

1979; Pergamon Press; Volume: 10; Issue: 6 Linguagem: Inglês

10.1016/0022-4731(79)90528-4

ISSN

1878-2353

Autores

E.V. YoungLai,

Tópico(s)

Hypothalamic control of reproductive hormones

Resumo

Isolated rabbit ovarian follicles were incubated with HCG and/or melatonin, serotonin, 5-hydroxy-dl-tryptophan or N-acetyl serotonin. Melatonin alone significantly decreased the accumulation of steroids elicited by HCG stimulation. Follicles did not bind labelled melatonin whereas the specific binding of [125I]-HCG was 4.11 pmol per mg protein.

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