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Revisão Revisado por pares
BIBTEX RIS

Cell-cycle-dependent translational control

2001; Elsevier BV; Volume: 11; Issue: 1 Linguagem: Inglês

10.1016/s0959-437x(00)00150-7

ISSN

1879-0380

Autores

Stéphane Pyronnet, Nahum Sonenberg,

Tópico(s)

RNA modifications and cancer

Resumo

Control of translation in eukaryotes occurs mainly at the initiation step. Translation rates in mammals are robust in the G1 phase of the cell cycle but are low during mitosis. These changes correlate with the activity of several canonical translation initiation factors, which is modulated during the cell cycle to regulate translation.

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