Synthesis of optically active 3-alkoxy-6-hydroxymethyl-6-methyl-2-cyclohexenone
1999; Elsevier BV; Volume: 10; Issue: 16 Linguagem: Inglês
10.1016/s0957-4166(99)00304-3
ISSN1362-511X
AutoresHiroaki Miyaoka, Yasuhiro Kajiwara, M Hara, Akira Suma, Yasuji Yamada,
Tópico(s)Analytical Chemistry and Chromatography
ResumoOptically active 3-alkoxy-6-hydroxymethyl-6-methyl-2-cyclohexenone and 6-acetoxymethyl-3-alkoxy-6-methyl-2-cyclohexenone were efficiently obtained by lipase-catalyzed kinetic resolution. (R)-6-Acetoxymethyl-3-(methoxymethoxy)-6-methyl-2-cyclohexenone was converted to the synthetic intermediate of cassiol.
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