Artigo Revisado por pares

Serological diagnosis of pneumococcal pneumonia

1979; Elsevier BV; Volume: 1; Linguagem: Inglês

10.1016/s0163-4453(79)80030-4

ISSN

1532-2742

Autores

B. Kaijser, Elisabeth Berntsson, Birger Trollfors,

Tópico(s)

Medical Imaging and Pathology Studies

Resumo

Two sensitive techniques for pneumococcal capsular antibody determination, radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) are available. The RIA-technique, however, is expensive and requires specific equipment and is, therefore, only available in a few centres. Evidence is produced to indicate that the ELISA technique is useful for the serological diagnosis of pneumococcal infection. It is inexpensive and does not require special equipment. Furthermore, antibody determination of the different immunological classes can be performed easily. To date, no detailed comparison between ELISA and RIA is published.

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