Artigo Revisado por pares

A Photocontrolled Molecular Switch Regulates Paralysis in a Living Organism

2009; American Chemical Society; Volume: 131; Issue: 44 Linguagem: Inglês

10.1021/ja903070u

ISSN

1943-2984

Autores

Usama Al-Atar, Rylan Fernandes, Bob Johnsen, David L. Baillie, Neil R. Branda,

Tópico(s)

Light effects on plants

Resumo

Using light to modulate biochemical agents in living organisms has a significant impact on photodynamic therapy and drug release. We demonstrate that a photoresponsive system can reversibly induce paralysis in nematodes as a model for living organisms when two different wavelengths of light are used to toggle the molecular switch between its two structural forms. This example illustrates how photoswitches offer great potential for advancing biomedical technologies.

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