‘Crosstalk’: a pivotal role for protein kinase C in modulating relationships between signal transduction pathways

1991; Wiley; Volume: 195; Issue: 1 Linguagem: Inglês

10.1111/j.1432-1033.1991.tb15671.x

ISSN

1432-1033

Autores

Miles D. Houslay,

Tópico(s)

Bioactive Compounds and Antitumor Agents

Resumo

European Journal of BiochemistryVolume 195, Issue 1 p. 9-27 Free Access 'Crosstalk': a pivotal role for protein kinase C in modulating relationships between signal transduction pathways Miles D. HOUSLAY, Corresponding Author Miles D. HOUSLAY Molecular Pharmacology Group, Department of Biochemistry, University of Glasgow, Scotland, UKCorrespondence to M. D. Houslay, Molecular Pharmacology Group, Department of Biochemistry, University of Glasgow, Glasgow G12 8QQ, UKSearch for more papers by this author Miles D. HOUSLAY, Corresponding Author Miles D. HOUSLAY Molecular Pharmacology Group, Department of Biochemistry, University of Glasgow, Scotland, UKCorrespondence to M. D. Houslay, Molecular Pharmacology Group, Department of Biochemistry, University of Glasgow, Glasgow G12 8QQ, UKSearch for more papers by this author First published: January 1991 https://doi.org/10.1111/j.1432-1033.1991.tb15671.xCitations: 247 This review is dedicated to the memory of my late technician, Andrew Wilson, whose premature death occurred on 28th June 1990. AboutSectionsPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abbreviations G-protein guanine nucleotide-binding regulatory protein Gs stimulatory G-protein of adenylate cyclase Gi inhibitory G-protein of adenylate cyclase protein kinase C calcium- and phospholipid-dependent protein kinase TPA 12-O-tetradecanoyl phorbol 13-acetate PGE, PGD, etc. prostaglandin type E, D, etc. PTH parathyroid hormone LH luteinizing hormone VIP vaso-intestinal peptide EGF epidermal growth factor GR1 glucagon receptor (putative type 1) GR2 glucagon receptor (putative type 2) GABAA receptor receptor for 4-aminobutyric acid Enzymes Adenylate cyclase (EC 4.6.1.1) alkaline phosphatase (EC 3.1.3.1) protein kinase C (EC 2.7.1.37) REFERENCES 1 Birnbaumer, L. (1973) Biochim. Biophys. Acta 300, 129– 158. CrossrefCASPubMedWeb of Science®Google Scholar 2 Birnbaumer, L., Abramowitz, J. & Brown, A. M. (1990) Biochim. Biophys. Acta 1031, 163– 224. 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