Familial parkinsonism, apathy, weight loss, and central hypoventilation
1988; Lippincott Williams & Wilkins; Volume: 38; Issue: 4 Linguagem: Inglês
10.1212/wnl.38.4.637
ISSN1526-632X
AutoresElena Roy, Jack E. Riggs, J. D. Martin, Roey Ringel, Ludwig Gutmann,
Tópico(s)Obstructive Sleep Apnea Research
ResumoWe report a third family with six members with features of the syndrome of familial parkinsonism, depression, weight loss, and central hypoventilation. Patients with this syndrome typically die suddenly, presumably from central respiratory failure. Following multiple respiratory arrests, one affected member was successfully managed with aggressive pulmonary care, tracheostomy, and intermittent home mechanical ventilation, which, combined with carbidopa/levodopa, allowed for a functional lifestyle with improvement in apathy, mobility, and nutritional status.
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