Cell Death in Cortical Development: How Much? Why? So What?
1996; Cell Press; Volume: 16; Issue: 4 Linguagem: Inglês
10.1016/s0896-6273(00)80089-6
ISSN1097-4199
Autores Tópico(s)Neuroscience and Neuropharmacology Research
ResumoSince Hamburger and Levi-Montalcini 1949 demonstrated that cell survival in the chick spinal cord could be regulated by the amount of neuronal target available, normal cell death has come to be an accepted feature of neuronal development (reviewed byCowan et al. 1984; Clarke 1990; Oppenheim 1991; Raff et al. 1993). Cell death is an inherently difficult process to measure, however, so that for most regions of the nervous system the total amount of cell death that normally occurs is not yet clear.
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