Artigo Revisado por pares

“Diplophage”: A bacteriophage of Diplococcus pneumoniae

1975; Elsevier BV; Volume: 63; Issue: 2 Linguagem: Inglês

10.1016/0042-6822(75)90329-3

ISSN

1096-0341

Autores

Maureen McDonnell, C Ronda-Laín, Alexander Tomasz,

Tópico(s)

Mycobacterium research and diagnosis

Resumo

Bacteriophage capable of infecting Diplococcus pneumoniae strain R36A was isolated from throat samples of human patients with upper respiratory symptoms. One of the isolates, "Diplophage 1" (Dp-1), was purified and characterized in more detail. The virus contains DNA, it has a polyhedral head, tail, and base plate. Pneumococci become completely resistant to Dp-1 if the choline residues of the teichoic acid are replaced by ethanolamine and other choline analogs. This phage may require the bacterial autolytic system for successful infection.

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