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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

The Complexity of Antibody-Dependent Enhancement of Dengue Virus Infection

2010; Multidisciplinary Digital Publishing Institute; Volume: 2; Issue: 12 Linguagem: Inglês

10.3390/v2122649

ISSN

1999-4915

Autores

María G. Guzmán, Susana Vázquez,

Tópico(s)

Viral Infections and Outbreaks Research

Resumo

Antibody-dependent enhancement (ADE) has been proposed as a mechanism to explain dengue hemorrhagic fever (DHF) in the course of a secondary dengue infection. Very recently, Dejnirattisai et al., 2010 [1], published an important article supporting the involvement of anti-prM antibodies in the ADE phenomenon. The complexity of ADE in the context of a secondary dengue infection is discussed here.

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